Scientists found that consuming the sugar alternative made of sucralose caused a person's sugar levels to peak at a higher level and in turn increase the amount of insulin a person produced.
Researchers said that while they did not fully understand the implications of the findings, they might suggest that Splenda could raise the risk of diabetes.
This is because regularly elevated insulin levels can lead to insulin resistance, which is a known path to type 2 diabetes.
'Our results indicate that this artificial sweetener is not inert - it does have an effect,' said Yanina Pepino, research assistant professor of medicine at the Washington School of Medicine in St. Louis, who led the study.
'And we need to do more studies to determine whether this observation means long-term use could be harmful.'
Sucralose is made from sugar, but once processed its chemical make up is very different. Gram for gram it is 600 times sweeter than table sugar.
The scientists analysed the effects of Splenda in 17 severely obese people who did not have diabetes and did not use artificial sweeteners regularly.
Participants had an average body mass index of just over 42. A person is considered obese when their BMI reaches 30.
Scientists gave subjects either water or dissolved sucralose to drink before they consumed glucose (sugar).
Read more: http://www.dailymail.co.uk/health/article-2333336/Could-artificial-sweetener-CAUSE-diabetes-Splenda-modifies-way-body-handles-sugar-increasing-insulin-production-20.html#ixzz2Uxe0l9Q7
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